Welcome to the CHO gene coexpression database

Chinese hamster ovary (CHO) is the most widely used mammalian cell type for production of recombinant therapeutic proteins. The recent publication of the CHO genome along with analysis of the transcriptome and proteome is shedding light on the underlying biological mechanisms of CHO behavior in the bioreactor. Knowledge gained from these data have thepotential to enhance these cell lines for the industrial production of therapeutics.

CGCDB aims to provide access to gene coexpression patterns derived from the microarray analysis of transcript expression during industrial cell culture of CHO. Users can access correlations between pairs of genes and between genes and CHO cell growth rate and cell specific productivity.

Browse GCGDB to select a gene of interest
Search database by gene or phenotype

Example output for gene-gene coexpression and gene-phenotype correlation

Qp
CDC20
MCM7
CIRBP
DHFR
Growth